Six botulinum toxin products have cosmetic uses on their FDA labels: Botox Cosmetic, Dysport, Xeomin, Jeuveau, Daxxify and Letybo. Each one smooths lines for a while by relaxing the muscle that creates them (FDA label for Botox Cosmetic). Botox Cosmetic has the widest label, with four cosmetic areas since neck (platysma) bands were added in October 2024 (FDA label for Botox Cosmetic). If you are comparing spas around Dallas, three questions matter: which product they inject, how they charge for it and whether the injector meets Texas rules. The sections below answer each from the product labels and the published research.
Mechanism
How a neurotoxin relaxes a muscle
Botox Cosmetic contains a purified botulinum toxin type A made by the bacterium Clostridium botulinum. After injection it splits SNAP-25, a protein the nerve ending needs to release acetylcholine. Without acetylcholine, the muscle gets a weaker signal to contract and moves less (FDA label for Botox Cosmetic).
The effect wears off. The label explains that the nerve can reinnervate the muscle, gradually undoing the effect, and puts the frown line result at roughly 3 to 4 months (FDA label for Botox Cosmetic). Keeping the result means returning for more treatment.
Two points people often miss:
- It relaxes; it does not fill. A neurotoxin reduces the movement behind a line. The labeled uses are for lines tied to muscle activity (FDA label for Botox Cosmetic).
- A unit means something different for each brand. Ten units of Botox are not ten units of Dysport. The labels for Botox Cosmetic, Dysport and Xeomin all state that their units cannot be compared with or converted to units of another botulinum toxin product (FDA label for Botox Cosmetic) (FDA label for Dysport) (FDA label for Xeomin).
Products
The six brands side by side
Every product here is a type A botulinum toxin. The approved cosmetic areas are where their labels part ways.
| Brand | Label company | Approved cosmetic areas | Other label notes |
|---|---|---|---|
| Botox Cosmetic | AbbVie | Frown lines, crow’s feet, forehead lines, platysma bands | Neck bands added October 2024 |
| Dysport | Ipsen (also distributed by Galderma) | Frown lines | For adults younger than 65; contains trace cow’s milk protein |
| Xeomin | Merz | Frown lines, crow’s feet, forehead lines | Toxin free of accessory proteins |
| Jeuveau | Evolus | Frown lines | |
| Daxxify | Revance | Frown lines | Toxin free of accessory proteins |
| Letybo | Hugel | Frown lines |
Labels used for the table: Botox Cosmetic, Dysport, Xeomin, Jeuveau, Daxxify, Letybo.
Area by area: every label covers frown lines, the vertical ”11s” between the eyebrows. Xeomin and Botox Cosmetic add crow’s feet and forehead lines. Neck bands appear on the Botox Cosmetic label and no other (FDA label for Botox Cosmetic) (FDA label for Xeomin). Using a product in an area its label leaves out is off-label. At the consultation, ask which brand will be used and whether its label includes the area you want treated.
Daxxify’s duration data
The SAKURA 1 and SAKURA 2 trials gave each patient a single 40-unit dose of Daxxify. Median time with frown lines rated none or mild was 24.0 weeks in one trial and 23.9 weeks in the other (SAKURA trial report). A median means half the patients fell short of that mark. Patients were followed for up to 36 weeks (SAKURA trial report). Per the label, Daxxify treatments should be spaced at least three months apart (FDA label for Daxxify).
Is Dysport faster than Botox?
The claim is common, but the Dysport label states no onset time for frown lines (FDA label for Dysport). For Botox Cosmetic, the label describes weakening that begins one to two days after the injection and increases over the first week (FDA label for Botox Cosmetic). If you are timing treatment before an event, ask your provider how much lead time to leave.
What to expect
Treatment day, doses and the following months
The label specifies a 30 to 33 gauge needle for Botox Cosmetic (FDA label for Botox Cosmetic). Appointment length and whether the spa uses ice or a numbing cream are questions for the practice.
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At the visit
The injection sites can be bruised, red, swollen, tender or sore. Anxiety or needle pain can bring on fainting or a dip in blood pressure (FDA label for Botox Cosmetic).
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Day of treatment
Instructions such as keeping your head upright or skipping a workout come from providers, not from the label. Follow the ones your provider gives.
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First week
For frown lines, the label describes muscle weakening that typically begins one to two days after injection and increases through the week. Side effects also tend to appear during this first week (FDA label for Botox Cosmetic).
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Check-in
Find out whether the spa schedules a review visit and whether any touch-up units are charged separately.
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3 to 4 months
This is roughly how long the frown line effect lasts. The label says dosing more often than every 3 months has no safety or effectiveness evaluation (FDA label for Botox Cosmetic).
Labeled Botox Cosmetic doses by area (FDA label for Botox Cosmetic):
- Frown lines (the 11s): 20 units in total, split as 4 units into each of 5 sites
- Crow’s feet: 24 units, meaning 12 on each side
- Forehead lines: 20 units on top of the 20 for frown lines, so 40 units together
- Frown lines, forehead lines and crow’s feet at one visit: 64 units
- Neck (platysma) bands: 26, 31 or 36 units, set by the number of bands
- Off-label areas (lip flip, bunny lines, chin dimpling, masseter, brow lift): the label gives no dose for these
- Underarm sweating: treated with BOTOX, the non-cosmetic product, at a labeled 100 units for severe primary axillary hyperhidrosis
Each other brand has its own unit scale, and none converts to Botox units.
Aftercare
Exercise, heat and sweating
Nothing in the Botox Cosmetic label addresses exercise, sweating or heat after an injection (FDA label for Botox Cosmetic). Ask your provider for their first-day guidance on all three and schedule workouts or time outside accordingly.
Safety
Side effects reported in the trials
Below are the most frequent side effects from the Botox Cosmetic trials, shown against placebo (FDA label for Botox Cosmetic).
| Area studied | Side effect | Placebo | Botox Cosmetic |
|---|---|---|---|
| Frown lines | Drooping eyelid | 0% | 3% |
| Frown lines | Pain in the face | 0% | 1% |
| Crow’s feet | Swollen eyelid | 0% | 1% |
| Forehead plus frown lines | Headache | 5% | 9% |
| Forehead plus frown lines | Drooping eyelid | 0% | 2% |
| Forehead plus frown lines | Drooping brow | 0% | 2% |
The label notes that most side effects begin in the first week after injection. Many resolve, but some persist for several months or more (FDA label for Botox Cosmetic). Across the two Daxxify phase 3 trials, pain where the needle went in (5.0% and 2.4%) and headache (7.0% and 5.9%) topped the treatment-related effects (SAKURA trial report).
Serious risks
All botulinum toxin products share an FDA boxed warning about the toxin effect spreading beyond where it was injected. Signs can start hours or weeks later: muscle weakness, double vision, drooping eyelids, or difficulty swallowing, speaking or breathing. Problems with swallowing and breathing can threaten life, and deaths have been reported (FDA label for Botox Cosmetic). The label says children treated for spasticity probably face the highest risk, and that at labeled cosmetic doses there are no definitive serious reports of distant spread (FDA label for Botox Cosmetic).
Anaphylaxis and other serious allergic reactions are also on the label, as are cardiovascular adverse events, including some deaths. People with existing heart disease are advised to use caution (FDA label for Botox Cosmetic). Any difficulty swallowing, speaking or breathing after treatment calls for emergency medical care.
Pregnancy and nursing
No one has established safety here. According to the Botox Cosmetic label, developmental risk in pregnant women has not been studied with adequate data, and animal studies found effects on fetal growth when the dose was toxic to the mother. On nursing, it says there are no data on whether the drug passes into breast milk or affects the infant (FDA label for Botox Cosmetic).
Tell your provider about a pregnancy, a possible pregnancy or breastfeeding. If a pregnancy turns out to have started before a treatment, let your OB/GYN know.
Who should not be treated, and who needs caution
Botox Cosmetic has two contraindications on its label (FDA label for Botox Cosmetic):
- Allergy to any botulinum toxin product or to an ingredient in the formulation
- Infection where the injection would go
Dysport adds a third: allergy to cow’s milk protein (FDA label for Dysport).
The label calls for caution or monitoring in these cases (FDA label for Botox Cosmetic):
- A nerve or muscle disorder such as ALS, myasthenia gravis or Lambert-Eaton syndrome
- Existing problems with swallowing or breathing
- Use of muscle relaxants, curare-like agents or aminoglycoside antibiotics, any of which can strengthen the toxin effect
- A different botulinum toxin product within the last several months
Evidence watch
The case for “preventative Botox”
Botox Cosmetic is approved to improve, for a time, the appearance of moderate to severe lines a person already has. The label makes no prevention claim (FDA label for Botox Cosmetic).
The study cited most often is a 2006 report about one set of identical twins. Over a 13-year span, the forehead and the area between the brows were injected about 2 to 3 times a year in one twin and only twice in the other. At the end, the frequently treated twin had no lines at rest in those areas, and the other twin did (Binder, 2006). A result from two people cannot tell anyone whether it applies to the wider population.
A better question for your provider is whether the lines you have today justify treatment.
Pricing
How Botox is priced in Dallas
Prices are set by each spa, and your total depends on the unit count. Get a quote from every practice you are considering. The area pages on this site list the same national average shown below.
The American Society of Plastic Surgeons puts the national average for a botulinum toxin treatment at $435 (ASPS). The number comes from plastic surgeons, ASPS does not state which year it covers, and it is not a Dallas med spa price.
Some spas charge per unit and others per area. Before booking, ask:
- How many units will I need, and what does each one cost?
- For a per-area price, how many units are included, and what is the charge for more?
- Which brand is this? Units from different brands do not compare.
Comparing Daxxify prices
Daxxify units do not line up with Botox units (FDA label for Daxxify). Compare the full price of the treatment instead of the unit price, and ask when you would likely need the next one.
Loyalty programs and memberships
Manufacturers may run patient rewards programs; ask whether one exists and whether the spa takes part. For a membership, weigh the monthly fee, the unit discount and the cancellation terms against how many treatments you plan per year.
Choosing a provider
Who may inject in Texas, and how to check
Under Texas Medical Board rules, injecting a substance for cosmetic purposes is a nonsurgical medical cosmetic procedure, which counts as practicing medicine and may be delegated and supervised (Tex. Admin. Code §169.25). These rules have been in effect since January 9, 2025 (Texas Medical Board).
| Who | What the rules or TDLR provide |
|---|---|
| Physician (MD/DO) | Performs a procedure classed as medicine and may delegate it (Tex. Admin. Code §169.25) |
| PA or APRN | Under physician delegation, may establish the practitioner-patient relationship; a physician, PA or APRN must be onsite or immediately available (Tex. Admin. Code §169.26) |
| Any delegated injector | Must have appropriate training, a written order and a written protocol they have signed (Tex. Admin. Code §169.26) (Tex. Admin. Code §169.27) |
| Esthetician | The license does not cover injecting botulinum toxin (TDLR) |
Conditions for a delegated injection:
- The practitioner-patient relationship comes first. It is set up before the procedure by a physician, or by a PA or APRN under that physician’s delegation (Tex. Admin. Code §169.26). The rule itself does not use the phrase “good faith exam,” though many spas do.
- A physician, PA or APRN is onsite or immediately available in case of an emergency (Tex. Admin. Code §169.26).
- There is a written order (Tex. Admin. Code §169.27) and a written protocol signed and dated by the injector (Tex. Admin. Code §169.26).
- Every public area and treatment room shows the delegating physician’s name and Texas license number (Tex. Admin. Code §169.28).
According to TDLR, Botox and filler injections are medical treatments given under a licensed physician’s order and delegation (TDLR).
Checking credentials
- Physicians and PAs: search the Texas Medical Board’s Look Up a License page. The result includes any Board action taken against the license holder (Texas Medical Board).
- Board certification: the American Board of Medical Specialties runs a lookup for patients, Certification Matters, linked from its Verify Certification page.
- RNs and APRNs: the Texas Board of Nursing offers license verification.
What to ask at the consultation
- How were you trained to inject cosmetic neurotoxins, and roughly how many treatments have you done?
- Which physician delegates here, and where are their name and license number posted?
- Who sets up my practitioner-patient relationship before I am treated?
- What brand will you use, and is my area on its FDA label?
- How many units are you planning, and what will the total be?
- Does the price include a follow-up visit, or are touch-up units extra?
- What will you do if I develop a drooping eyelid or another side effect?
Warning signs
- No one can name the delegating physician
- No physician name or Texas license number is posted in public areas and treatment rooms (Tex. Admin. Code §169.28)
- You are treated before any practitioner-patient relationship exists (Tex. Admin. Code §169.26)
- The injector is an esthetician (TDLR)
- No one asks about your health history or medicines
- The quote has no unit count, or you are pushed with “today only” pricing
Treatment Areas